{"product_id":"methylation-panel-by-genova-diagnostics","title":"Methylation Panel with or without genetics testing","description":"\u003cmeta charset=\"UTF-8\"\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003eA Personalized Approach to Healthy Aging\u003c\/h3\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe Methylation Panel is an innovative test designed to offer insight into the critical biochemical methylation pathway. Methylation metabolites are measured in plasma, and genetic single nucleotide polymorphisms (SNPs) are analyzed via buccal swab. Patient results are synthesized on a front-page Interpretation-at-a-Glance (IAAG) graphic for quick methylation status assessment. Within the report, results are shown in a methylation pathway graphic to provide a clear understanding of the biochemistry involved.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003ch4 data-mce-fragment=\"1\"\u003eWhat is Methylation?\u003c\/h4\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMethylation is a chemical process that happens billions of times per second in every cell of the body.\u003ca href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1007\/s10545-016-9972-7\" data-mce-fragment=\"1\" data-mce-href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1007\/s10545-016-9972-7\" target=\"_blank\"\u003e\u003csup data-mce-fragment=\"1\"\u003e1\u003c\/sup\u003e\u003c\/a\u003e Methyl groups are transferred and donated between many different molecules which change their structure and function. Methyl groups act like billions of switches which turn genes on or off, help regulate mood, detoxify hormones, produce energy, and promote healthy aging.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eVitamins, minerals, and amino acids from the diet are needed to keep this process running smoothly.\u003c\/strong\u003e There are also genetic factors and oxidative stressors which can affect how well this pathway works.\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3806315\/\" data-mce-fragment=\"1\" data-mce-href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3806315\/\" target=\"_blank\"\u003e\u003csup data-mce-fragment=\"1\"\u003e2\u003c\/sup\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003ch4 data-mce-fragment=\"1\"\u003eWhy is Methylation important?\u003c\/h4\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eMethylation is needed to create DNA and RNA and regulate gene expression.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eIt helps make creatine, which is needed for skeletal muscle contraction.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eMethylation is involved in basic energy production, fat metabolism, immune responses, vascular health, and cell membrane repair.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eIt produces and metabolizes neurotransmitters to regulate mood.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eMethylation also works to neutralize toxins and hormones.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eWhich patients can benefit from the Methylation Panel?\u003c\/h4\u003e\n\u003cp\u003eBecause of its all-encompassing role in basic human physiology, the range of symptoms associated with methylation defects is broad. The Methylation Panel can offer insight in patients with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003equestionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)\u003csup\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3860421\/\" target=\"_blank\"\u003e3\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19387915\/\" target=\"_blank\"\u003e4\u003c\/a\u003e,\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3319153\/\" target=\"_blank\"\u003e5\u003c\/a\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ecancer risk\u003csup\u003e\u003ca href=\"https:\/\/academic.oup.com\/advances\/article\/3\/6\/755\/4557945\" target=\"_blank\"\u003e6\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20663323\/\" target=\"_blank\"\u003e7\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26254344\/\" target=\"_blank\"\u003e8\u003c\/a\u003e,\u003ca href=\"https:\/\/tgh.amegroups.com\/article\/view\/4349\/5144\" target=\"_blank\"\u003e9\u003c\/a\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ecardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)\u003csup\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3542324\/\" target=\"_blank\"\u003e10\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16601863\/\" target=\"_blank\"\u003e11\u003c\/a\u003e,\u003ca href=\"https:\/\/febs.onlinelibrary.wiley.com\/doi\/full\/10.1016\/j.febslet.2009.03.038\" target=\"_blank\"\u003e12\u003c\/a\u003e,\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2854908\/\" target=\"_blank\"\u003e13\u003c\/a\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003epsychiatric and mood disorders (schizophrenia, autism, bipolar disorder, anxiety, depression)\u003csup\u003e\u003ca href=\"https:\/\/academic.oup.com\/advances\/article\/3\/6\/755\/4557945\" target=\"_blank\"\u003e6\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18950248\/\" target=\"_blank\"\u003e14\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22762295\/\" target=\"_blank\"\u003e15\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19079880\/\" target=\"_blank\"\u003e16\u003c\/a\u003e,\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4203003\/\" target=\"_blank\"\u003e17\u003c\/a\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eneurologic disorders (Parkinson’s disease, cognitive decline)\u003csup\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19679632\/\" target=\"_blank\"\u003e18\u003c\/a\u003e,\u003ca href=\"https:\/\/alzres.biomedcentral.com\/articles\/10.1186\/s13195-017-0270-x\" target=\"_blank\"\u003e19\u003c\/a\u003e,\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27431367\/\" target=\"_blank\"\u003e20\u003c\/a\u003e\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003echronic fatigue\u003ca href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0104757\" target=\"_blank\"\u003e\u003csup\u003e21\u003c\/sup\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003eHow are the results of the Methylation Panel helpful?\u003c\/h4\u003e\n\u003cp\u003eThe Methylation Panel can uncover needs for nutritional support such as amino acids, vitamins, and minerals. Knowing this can help guide dietary and nutraceutical treatment plans. Additionally, knowing genetic predispositions can help focus supplementation to override potential methylation defects.\u003c\/p\u003e","brand":"Genova Diagnostics","offers":[{"title":"With Genetics","offer_id":40671184584746,"sku":"","price":599.0,"currency_code":"USD","in_stock":true},{"title":"Without Genetics","offer_id":40671184617514,"sku":"","price":349.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1334\/3567\/files\/GeneticTest.png?v=1780027920","url":"https:\/\/metabolicnutrients.com\/products\/methylation-panel-by-genova-diagnostics","provider":"MetabolicNutrients.com","version":"1.0","type":"link"}